The REACH Regulation (EC No 1907/2006), implemented by the European Chemicals Agency (ECHA), provides public access to regulatory dossiers submitted by industry for chemicals manufactured or imported into the European Union.
These dossiers are prepared in the standardized IUCLID format (International Uniform Chemical Information Database), which structures physicochemical, toxicological and ecotoxicological study summaries according to harmonized reporting templates.
What has been done ?
Few sections of REACH dossiers have been downloaded locally (from ECHA website here) and integrated in OpenChemFacts in-house models through a Python package (here).
These sections are the ones providing aquatic ecotoxicity test results :
Then OpenChemFacts transformed these raw information to derive EC10eq values.
These aggregated indicators are then made available on OpenChemFacts platform so that HC20 and EffectFactor(EF) values can be derived for as many chemicals as possible.
Data transformation
The extracted ecotoxicological endpoints are processed locally through :
derivation of hazard indicators (HC20, Effect Factors).
OpenChemFacts publishes only derived indicators and processed outputs, not the original structured IUCLID datasets.
Database rights
OpenChemFacts does not reproduce the whole or a substantial part of the ECHA databases. The platform provides transformed and value-added scientific outputs for a specific indicator (aquatic ecotoxicity) derived from publicly accessible information.
Certain identifiers (e.g., CAS numbers) may be subject to third-party intellectual property rights. OpenChemFacts does not claim ownership of such identifiers.