Ecotox (US EPA)

The ECOTOX database, developed by the U.S. EPA, is publicly available application that provides information on adverse effects of single chemical stressors to ecologically relevant aquatic and terrestrial species.

Data are curated from scientific literature after an exhaustive search protocol. Compiled from over 53,000 references, ECOTOX currently includes over one million test records covering more than 13,000 aquatic and terrestrial species and 12,000 chemicals.

Detailed information ⇒ https://www.epa.gov/comptox-tools/ecotoxicology-ecotox-knowledgebase-resource-hub

What has been done ?

ECOTOX datasets have been collected locally through a SQLite database using an R package (https://pepijn-devries.github.io/ECOTOXr/articles/ecotox-schema.html).

Data Pipeline (summary)

Dataset	CAS	Tests	Results
All chemicals in ECOTOX	18 481	723 445	1 218 861
Chemicals with tests results in EC10eq	10 278	392 821	694 662
Chemicals with relevant endpoints	7 182	244 074	488 837
Chemicals with valid results (filtered)	5 116	173 977	328 430
Only one EC10eq result per test	3 617	87 358	87 358